IgAN explained
EPIDEMIOLOGY
IgA nephropathy (IgAN) is the most prevalent type of primary glomerulonephritis worldwide1–3
Global distribution of patients with IgAN in some key regions worldwide4
IgAN prevalence* shown as the percentage of biopsy-proven primary glomerulonephritis4
Image adapted from Lai KN, et al. 2016
IgAN affects:2,5
2.5 per 100,000 people worldwide on average†
People of all ages and ethnicities, although more common in men and young adults
Young adults who are otherwise healthy and often asymptomatic
While a rare disease, IgAN occurs in a variety of people worldwide.
References & footnotes
Footnotes
*Exact prevalence may vary due to country-specific policies for healthcare and biopsy requirements
†Average incidence of IgAN based on 40 studies of incidence of primary glomerulonephritis from Europe, North and South America, Canada, Australia and the Middle East published between 1980–20102
Abbreviations
IgAN, IgA nephropathy; KDIGO, Kidney Disease: Improving Global Outcomes.
References
- Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group. KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases. Kidney Int. 2021; 100:S1−S276.
- McGrogan A, et al. The incidence of primary glomerulonephritis worldwide: a systematic review of the literature. Nephrol Dial Transplant. 2011; 26:414–30.
- Rodrigues JC, et al. CJASN Glomerular Disease Education Series:IgA Nephropathy. Clin J Am Soc Nephrol. 2017; 12:677–86.
- Lai KN, et al. IgA nephropathy. Nat Rev Dis Primers. 2016; 2:16001.
- Yeo SC, et al. Is immunoglobulin A nephropathy different in different ethnic populations? Nephrology. 2019; 24:885–95.
HQ-SPT-2500011 | Date of preparation: February 2025