CKD‑aP
On the surface, Chronic Kidney Disease-associated Pruritus (formerly referred to as uremic pruritus) is just an itch.
But for patients living with CKD-associated Pruritus, the consequences are much more.1-6
CKD‑aP may be affecting your patients’ quality of life, mental health and even life expectancy.1-6

CKD-associated Pruritus impacts 67% of haemodialysis patients, with 37% of patients reportedly being moderately to extremely bothered by CKD-associated Pruritus.6
“STILL, THERE ARE TIMES WHEN MY ITCHING FEELS OVERPOWERING, WHEN I SAY TO MYSELF IT’S REALLY TERRIBLE RIGHT NOW.”
– CKD-associated Pruritus patient on haemodialysis, Germany
The itch with life-changing consequences
CKD patients undergoing haemodialysis already have a poor quality of life, which is exacerbated by CKD-associated Pruritus.1-3 Uncover how CKD-associated Pruritus could be affecting your haemodialysis patients’ sleep quality, social relationships and mental health.
“I’M SCRATCHING ALL THE TIME, YOU CAN’T HELP IT. I CAN’T SLEEP AT NIGHT BECAUSE IT’S THERE TWENTY-FOUR HOURS A DAY.”
– CKD-associated Pruritus patient on haemodialysis, UK

The impact of CKD-associated Pruritus lies beneath the surface
CKD-associated Pruritus can have a serious impact on health outcomes as well as higher drug utilisation.1,5,6 Look beneath the surface to discover the consequences of CKD-associated Pruritus.
“SOMETIMES I COULD JUST LITERALLY SCRATCH MYSELF TO DEATH”
– CKD-associated Pruritus patient on haemodialysis, Australia

Managing CKD-associated Pruritus - a challenge worth taking on
Management of CKD-associated Pruritus, should be an essential part of treatment for all patients undergoing haemodialysis and suffering from CKD-associated Pruritus.7 Help your patients make informed choices about their treatment options for CKD-associated Pruritus.
“THE REAL CHALLENGE WAS TO FIND THE TREATMENT THAT WORKED FOR ME”
– CKD-associated Pruritus patient on haemodialysis, Australia
References & footnotes
References
- Ramakrishnan K, Bond TC, Claxton A, et al. Clinical characteristics and outcomes of end-stage renal disease patients with self-reported Pruritus symptoms. Int J Nephrol Renovasc Dis. (2013);7:1–12.
- Shirazian S, Aina O, Park Y, et al. Chronic kidney disease-associated Pruritus: impact on quality of life and current management challenges. Int J Nephrol Renovasc Dis. (2017);10:11–26.
- Tsai YC, Hung CC, Hwang SJ, et al. Quality of life predicts risks of end-stage renal disease and mortality in patients with chronic kidney disease. Nephrol Dial Transplant. (2010);25:1621–1626.
- Pisoni R, Wikström B, Elder S, et al. Pruritus in haemodialysis patients: international results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant. (2006);21:3495–3505.
- Narita I, Alchi B, Omori K, et al. Etiology and prognostic significance of severe uremic Pruritus in chronic hemodialysis patients. Kidney Int. (2006);69(9):1626–1632.
- Sukul N, Karaboyas A, Csomor P, et al. Self-reported Pruritus and clinical, dialysis-related, and patient-reported outcomes in hemodialysis patients. Kidney Medicine. (2020);3(1):42–53.e1.
- Millington G, Collins A, Lovell C, et al. British Association of Dermatologists’ guidelines for the investigation and management of generalized Pruritus in adults without an underlying dermatosis, 2018. Br J Dermatol. (2018);178(1):34–60.

